Industry 4.0 is the adoption of computers and automation systems supported by data and machine learning in the supply chain and manufacturing segment. Industry 4.0 is compelling to redesign organizations whole supply chain. Digitization of supply chain is facilitated on the shoulders of Autonomous robots, Horizontal and Vertical system Integration, Simulation, The industrial internet of things, Cyber security, Additive manufacturing, the Cloud, Augmented reality, Big data, and analytics. Combining all the above technologies are helping companies to develop, change and optimize their supply chain and manufacturing.