Diet and lifestyle can help reduce calcium oxalate build up in the kidneys and urine and so can kidney medicines, medications and supplements. Drinking too little water is a major factor contributing to calcium oxalate crystals. Drinking extra water dilutes the substances in urine that lead to calcium oxalate crystals. Strive to drink enough fluids to pass 1 ½ to 2 liters of urine a day, which is roughly six to eight standard 8-ounce cups.
