Breast Cancer Genetic Screening:
Breast cancer, as the name suggests, takes its origin from the breasts in the form of lumps and spreads its wings from there to different parts of the body. It is a dangerous disease and can hamper the health and life of an individual; in certain cases may even lead to the death of an individual. As per the research studies, a considerable decline in the number of deaths pertaining to breast cancer has been observed. This has been possible due to early detection of breast cancer genes which has surged the process of breast cancer diagnosis leading to lower fatality rates. Early detection helps in following a more personalized approach towards the patient and also helps the doctor in designing effective treatment plans.
Knowing BRCA Genes:
Breast Cancer genes (BRCA) play a crucial role in early detection of breast cancer. These genes function normally in an individual and bear the properties of tumour suppressor genes. These genes also play a role in DNA repair mechanism. In short, they are important in the functioning of the body. However, any mutation occurring in these genes modifies the functioning of these genes and directs the functions of the body in the development of cancer. Mutations occurring in BRCA1 gene leads to the development of Breast cancer while mutations in BRCA2 may result in ovarian cancer in addition to breast cancer. These heritable changes if passed on to the child, increase the risk of developing cancer during the lifetime of the individual. Breast cancer is most commonly noticed in females. However, to a certain extent, males are also affected by breast cancer.
BRCA Screening in India:
Breast cancer screening is offered by some genetic testing diagnostic labs across the nation. One of the thought leaders in the field of genetic testing, Genes2Me offers BRCA test using advanced Next-generation sequencing technology. In addition to BRCA genes, this testing methodology also screens for additional genes which may increase the risk of breast, ovarian and pancreatic cancer. BRCA test offered by Genes2Me comes with pre and post genetic counselling options which can help the patient in understanding the test in a detailed manner and also helps in understanding the reports post-test results. With exceptional sensitivity and accuracy, BRCA test turnaround time is 3-4 weeks from the date of sample collection. A trained and certified genetic counsellor helps the patient to convert reports into meaningful results.
BRCA1 and BRCA2 Test Cost in India:
BRCA genes genetic screening cost varies in different parts of the country. An approximate price range exists between ₹15000-₹30,000. This cost can be negotiated depending upon the technology used and the number of genes under consideration.
Early detection is the key to prevent breast cancer. Knowing the mutation present in BRCA genes, one can reduce the risk of developing breast cancer during the lifetime. If the results come out to be positive, the doctor can plan a personalized approach for the purpose of treatment and diagnosis.
For more details, please visit www.genes2me.com or call 1800-121-4030, 8800821778.
Genetic Mutations and its causes:
Genes make proteins which are responsible for the proper functioning of the body. The process of translation processes the proteins. Any hindrance in this process leads to faulty production of proteins which in turn results in the development of severe health complication or disease in an individual. These hindrances can be called as genetic mutations. Mutations are usually defined as certain changes in the DNA carried by genes due to external or internal factors. These mutations alter the normal functioning of the gene and results in the development of genetic disorders, diseases and chromosomal abnormalities. Lifestyle changes and diet pattern may also cause certain mutation the genetic material of an individual resulting in severe health diseases.
BRCA Mutation and Genetic Screening:
BRCA genes are present normally in an individual and function as tumour suppressor genes. These genes do not allow the development of tumour in the body of the individual. These genes participate in DNA repair mechanism and prevent any kind of alteration in the structure of DNA. However, the functioning of BRCA genes changes if they are get altered due to genetic mutation. Any mutation in the BRCA genes changes the behaviour of genes and these genes instead of preventing the growth of a tumour; they help in the development of breast and ovarian cancer in the body of females. Even males also have an equal chance of developing breast cancer. Screening for genetic mutations in BRCA genes using genetic testing can help the doctors in early diagnosis of breast cancer. If an individual is found to be BRCA positive, the individual may be at high risk for developing breast cancer. At this point of time, the individual can meet his physician and discuss the changes that need to be adapted in order to lower down the risk of breast cancer.
Genetic testing and BRCA Check:
BRCA testing is crucial as it helps in estimating the risk of an individual for the development of breast and ovarian cancer. Different diagnostic labs present across the nation conduct BRCA genetic testing. Very few of them are recognized and provide reliable and accurate results. Genes2Me, one of recognized genetic testing laboratory offering solutions in advanced molecular diagnostics, provide BRCA testing for BRCA1 and BRCA2 genes. The company has a dedicated BRCA panel which screens for mutated BRCA genes in the genome of an individual. Using Next-Generation Sequencing technology, the genome of the individual is scanned, and BRCA mutated genes are identified. An advanced panel of BRCA also focuses on other genes other than BRCA that may put an individual at risk for the development of breast cancer. The test offers exceptional sensitivity, specificity and accuracy in the delivery of results. Pre and post genetic counselling options are provided by Genes2Me so that customers can know meaningful findings from the test reports. The counsellor guides the individual with preventive strategies and also help in estimating the risk of Breast cancer in the family.
Early diagnosis using BRCA genetic testing can help in estimating the risk of breast and ovarian cancer and can also help the doctors in designing effective treatment strategies.
